Increased Risk of Cardiovascular Disease in Young Women Following Gestational Diabetes Mellitus
نویسندگان
چکیده
OBJECTIVE To determine whether women with gestational diabetes mellitus (GDM) have an increased risk of cardiovascular disease (CVD) following pregnancy. RESEARCH DESIGN AND METHODS All women aged 20-49 years with live births between April 1994 and March 1997 in Ontario, Canada, were identified. Women with GDM were matched with 10 women without GDM and were followed for CVD. RESULTS The matched cohorts included 8,191 women with GDM and 81,262 women without GDM. Mean age at entry was 31 years, and median follow-up was 11.5 years. The hazard ratio for CVD events was 1.71 (95% CI 1.08-2.69). After adjustment for subsequent type 2 diabetes, the hazard ratio was attenuated (1.13 [95% CI 0.67-1.89]). CONCLUSIONS Young women with GDM had a substantially increased risk for CVD compared with women without GDM. Much of this increased risk was attributable to subsequent development of type 2 diabetes.
منابع مشابه
Gestational diabetes and cardiovascular risk Increased risk of cardiovascular disease in young women following gestational diabetes Gestational diabetes and cardiovascular risk
متن کامل
Comparing Carotid Intima-Media Thicknessin Women with and Without Gestational Diabetes Mellitus
Background & Aims: Women with history of gestational diabetes mellitus (GDM) are at risk for developing cardiovascular disease and metabolic syndrome. Carotid intima-media thickness (CIMT) is noninvasive marker of sub clinical atherosclerosis assessment. The aim of the present study was to assess relationship between GDM and increased CIMT. Methods: Twenty women with previous history of GDM and...
متن کاملDetermination the relationship between Periodontal disease and Gestational Diabetes Mellitus in pregnant women referred to selected public health centers in Mashhad, 2011
Introduction: Diabetes is the most common medical complication in pregnancy. Various risk factors have been mentioned for gestational diabetes, but just a few studies have assessed a relationship between periodontal disease and gestational diabetes. This study was conducted to determine the relationship between periodontal disease and gestational diabetes in clients of selected health- care cen...
متن کاملرابطهی مصرف سیگار با بروز دیابت بارداری
Background and Objective: Diabetes Mellitus is a metabolic disease and the most prevalent disorder in pregnancy. Gestational diabetes mellitus is a kind of diabetes that is recognized in pregnancy. Many risk factors have been recognized for gestational diabetes mellitus. Determining new risk factors help to identify women who are at risk for diabetes. This research was conducted in order to det...
متن کاملP-167: Association between Pregnancy Dietary Iron Intake and Gestational Diabetes Mellitus
Background: Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications affecting approximately 7% of all pregnancies and up to 14% of pregnancies in high-risk populations. Although, dietary iron intake is one of preventive factors for Iron deficiency which leads to less preterm delivery, prematurity, and SGA but iron is a strong pro-oxidant and high body iron levels c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Diabetes Care
دوره 31 شماره
صفحات -
تاریخ انتشار 2008